Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | APEX1 | P27695 | 2/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028251 | 0.80 | BRD4 (0.40) | BRD4BRD2PIK3CDLMNAALDH1A1 | |
| SCHEMBL6606439 | 0.77 | BRD4 (0.40) | BRD4BRD2PIK3CDLMNAALDH1A1 | |
| SCHEMBL22081453 | 0.76 | BRD4 (0.36) | BRD4BRD2PIK3CDLMNATSHR | |
| SCHEMBL10093754 | 0.74 | BRD4 (0.41) | BRD4BRD2PIK3CDLMNAMAPK1 | |
| SCHEMBL6608794 | 0.74 | BRD4 (0.38) | BRD4BRD2PIK3CDLMNAALDH1A1 | |
| SCHEMBL21465976 | 0.73 | BRD4 (0.40) | BRD4BRD2PIK3CDLMNAALDH1A1 | |
| SCHEMBL4508963 | 0.73 | BRD4 (0.40) | BRD4BRD2PIK3CDLMNAALDH1A1 | |
| SCHEMBL25988587 | 0.72 | BRD4 (0.39) | BRD4BRD2PIK3CDLMNAALDH1A1 | |
| SCHEMBL19918791 | 0.72 | BRD4 (0.39) | BRD4BRD2PIK3CDLMNAALDH1A1 | |
| SCHEMBL19106731 | 0.70 | PIK3CD (0.47) | BRD4BRD2PIK3CDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122769-A1 | SILOXANE COMPOUND AND A METHOD FOR PREPARING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-04-29 | — | — | US | disclosed |
| EP-3663303-A1 | SILOXANE COMPOUND AND PRODUCTION METHOD FOR SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2020-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122769-A1 | SILOXANE COMPOUND AND A METHOD FOR PREPARING THE SAME | HAO2, SEM1, MSMO1 | BRD4 4845/4885BRD2 4300/4885PIK3CD 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.