Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22082536 | 1.00 | LMNA (0.39) | LMNATSHRALDH1A1MAPK1NT5E | |
| SCHEMBL22082538 | 1.00 | LMNA (0.39) | LMNATSHRALDH1A1MAPK1NT5E | |
| SCHEMBL15579331 | 0.85 | MAOB (0.48) | LMNACNR2 | |
| SCHEMBL1094783 | 0.81 | LMNA (0.62) | LMNATSHRALDH1A1MAPK1NT5E | |
| SCHEMBL4877111 | 0.81 | HIF1A (0.48) | LMNATSHRALDH1A1MAPK1MAPT | |
| SCHEMBL1094781 | 0.81 | LMNA (0.62) | LMNATSHRALDH1A1MAPK1NT5E | |
| SCHEMBL1093539 | 0.81 | LMNA (0.62) | LMNATSHRALDH1A1MAPK1NT5E | |
| SCHEMBL24355251 | 0.79 | TSHR (0.42) | LMNATSHRALDH1A1MAPK1NT5E | |
| SCHEMBL5068688 | 0.79 | BRD4 (0.45) | LMNATSHRALDH1A1MAPTMEN1 | |
| SCHEMBL24355244 | 0.79 | TSHR (0.42) | LMNATSHRALDH1A1MAPK1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020115190-A1 | NOVEL ANTIBACTERIAL 3\"-DERIVATIVES OF 4,6-DISUBSTITUTED 2,5-DIDEOXYSTREPTAMINE AMINOGLYCOSIDE ANTIBIOTICS | AGILEBIOTICS B.V. (NL) | 2020-06-11 | — | — | WO | disclosed |