Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22082538 | 0.81 | LMNA (0.39) | HIF1ATSHRKDM4EALOX15TDP1 | |
| SCHEMBL22081099 | 0.81 | LMNA (0.39) | HIF1ATSHRKDM4EALOX15TDP1 | |
| SCHEMBL22082536 | 0.81 | LMNA (0.39) | HIF1ATSHRKDM4EALOX15TDP1 | |
| SCHEMBL5597741 | 0.80 | ESR1 (0.46) | HIF1ATAAR1NFKB1HTR3ATSHR | |
| SCHEMBL25309981 | 0.79 | MEN1 (0.49) | CA2LMNAMAPK1MEN1CA1 | |
| SCHEMBL19716560 | 0.79 | PARP10 (0.46) | TSHRTDP1CA2CYP3A4BLM | |
| SCHEMBL19735013 | 0.79 | HDAC3 (0.45) | LMNAALDH1A1 | |
| SCHEMBL5068688 | 0.79 | BRD4 (0.45) | NFKB1TSHRKDM4EALOX15APEX1 | |
| SCHEMBL19717863 | 0.79 | BRD4 (0.45) | NFKB1TSHRKDM4EALOX15APEX1 | |
| SCHEMBL5068690 | 0.79 | BRD4 (0.45) | NFKB1TSHRKDM4EALOX15APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023237603-A1 | RECYCLING METHOD FOR PRODUCING A POLYAMIDE COMPOUND | BASF SE (DE) | 2023-12-14 | — | — | WO | claimed |
| US-4407815-A | AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1983-10-04 | — | — | US | claimed |
| WO-2023237603-A1 | RECYCLING METHOD FOR PRODUCING A POLYAMIDE COMPOUND | BASF SE (DE) | 2023-12-14 | — | — | WO | disclosed |
| US-20090047699-A1 | FLUOROGENIC ENZYME ACTIVITY ASSAY METHODS AND COMPOSITIONS USING FRAGMENTABLE LINKERS | APPLIED BIOSYSTEMS INC. (US) | 2009-02-19 | — | — | US | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |
| CN-1136893-C | Medicine for curing diabetes | 王显勇 | 2004-02-04 | — | — | CN | disclosed |
| CN-1326771-A | Medicine for curing diabetes | WANG XIANYONG (CN) | 2001-12-19 | — | — | CN | disclosed |
| EP-0067518-B1 | MODIFIED BETA-LACTAM COMPOUNDS | BEECHAM GROUP PLC (GB) | 1985-08-21 | — | — | EP | disclosed |
| US-4517124-A | REACTION OF A MERCAPTAN TO FORM ANTIVIOTIC | BEECHAM GROUP LIMITED (GB) | 1985-05-14 | — | — | US | disclosed |
| EP-0046363-B1 | PROCESS FOR THE PREPARATION OF 2-THIO PENEM DERIVATIVES AND INTERMEDIATES THEREFOR | BEECHAM GROUP PLC (GB) | 1984-11-14 | — | — | EP | disclosed |
| EP-0034443-B1 | BETA-LACTAM ANTIBACTERIAL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | disclosed |
| US-4463010-A | 1-Aza-[3.2.0]-bicycloheptane-2-carboxylic acid, ester or salt thereof | BEECHAM GROUP P.L.C. (GB) | 1984-07-31 | — | — | US | disclosed |
| US-4407815-A | AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1983-10-04 | — | — | US | disclosed |
| US-4387051-A | β-Lactam antibiotics, their preparation and their use in pharmaceutical compositions | BEECHAM GROUP LIMITED (GB) | 1983-06-07 | — | — | US | disclosed |
| EP-0073100-A1 | Beta-lactam compounds, their preparation and their use | BEECHAM GROUP PLC (GB) | 1983-03-02 | — | — | EP | disclosed |
| EP-0046363-A1 | Process for the preparation of 2-thio penem derivatives and intermediates therefor | BEECHAM GROUP PLC (GB) | 1982-02-24 | — | — | EP | disclosed |
| EP-0034443-A2 | Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-08-26 | — | — | EP | disclosed |
| EP-0028497-A1 | Beta-lactam antibiotics, their preparation and their use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047699-A1 | FLUOROGENIC ENZYME ACTIVITY ASSAY METHODS AND COMPOSITIONS USING FRAGMENTABLE LINKERS | BCHE, SI, ENGASE | HIF1A 4643/4885TAAR1 3776/4885NFKB1 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.