Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10880212 | 0.85 | CYP1A2 (0.46) | CYP1A2CYP2C9KEAP1NFE2L2CYP2D6 | |
| SCHEMBL2372942 | 0.85 | CYP1A2 (0.46) | CYP1A2CYP2C9KEAP1NFE2L2CYP2D6 | |
| SCHEMBL2371928 | 0.85 | CYP1A2 (0.46) | CYP1A2CYP2C9KEAP1NFE2L2CYP2D6 | |
| SCHEMBL11136988 | 0.85 | CYP1A2 (0.46) | CYP1A2CYP2C9KEAP1NFE2L2CYP2D6 | |
| SCHEMBL11006416 | 0.85 | MAPT (0.54) | CYP1A2CYP2C9KEAP1NFE2L2CYP2D6 | |
| SCHEMBL16384453 | 0.85 | MAPT (0.48) | CYP1A2CYP2C9KEAP1NFE2L2CYP2D6 | |
| SCHEMBL378835 | 0.85 | CYP1A2 (0.46) | CYP1A2CYP2C9KEAP1NFE2L2CYP2D6 | |
| Putrescine SCHEMBL10612802 | 0.85 | KIF11 (0.48) | CYP1A2CYP2D6MAPTKMT2ATSHR | |
| SCHEMBL7196195 | 0.84 | CES1 (0.50) | CYP1A2CYP2C9KEAP1NFE2L2CYP2D6 | |
| Methylamine SCHEMBL11005397 | 0.82 | MAPT (0.55) | CYP1A2CYP2C9KEAP1NFE2L2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118833-B1 | SUBSTITUTED DIAMIDES OF PHENYLHYDROXY-THIOMALONIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1986-04-02 | — | — | EP | claimed |
| JP-55000347-A | — | — | None | — | — | JP | disclosed |
| EP-2785679-B1 | MANDELIC ACID CONDENSATION POLYMERS | UNIV RUSH MEDICAL CENTER (US) | 2019-01-09 | — | — | EP | disclosed |
| CN-107266306-A | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | 拜耳知识产权有限责任公司 | 2017-10-20 | — | — | CN | disclosed |
| US-20170143757-A1 | MANDELIC ACID CONDENSATION POLYMERS | UNIV RUSH MEDICAL CENTER (US) | 2017-05-25 | — | — | US | disclosed |
| CN-103980109-B | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | 拜尔农作物科学股份公司 | 2017-05-03 | — | — | CN | disclosed |
| US-9527793-B2 | Mandelic acid condensation polymers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-12-27 | — | — | US | disclosed |
| US-20140371310-A1 | MANDELIC ACID CONDENSATION POLYMERS | RUSH UNIVERSITY MEDICAL CENTER | 2014-12-18 | — | — | US | disclosed |
| EP-2785679-A1 | MANDELIC ACID CONDENSATION POLYMERS | Rush University Medical Center (US) | 2014-10-08 | — | — | EP | disclosed |
| US-8664428-B2 | Method for producing (2,4-dimethylbiphenyl-3-yl)acetic acids, the esters thereof and intermediate compounds | BAYER CROPSCIENCE AG (DE) | 2014-03-04 | — | — | US | disclosed |
| EP-0363034-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1995-01-04 | — | — | EP | disclosed |
| CN-1091633-A | Use aryl-, heteroaryl-and alkyltartronic acids as therapeutic agent | DOMPE FRAMACEUTICI S P A (IT) | 1994-09-07 | — | — | CN | disclosed |
| EP-0605404-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1994-07-06 | — | — | EP | disclosed |
| US-5212313-A | For polyester | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-18 | — | — | US | disclosed |
| US-5084580-A | Aniline dyes for polyester fabrics to give green and blue color | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| EP-0363034-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1990-04-11 | — | — | EP | disclosed |
| US-4698333-A | Use of substituted malonic acid derivatives as agents for combating pests | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-06 | — | — | US | disclosed |
| US-4562185-A | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | disclosed |
| EP-0061219-A1 | p-Hydroxyphenylmalonic acid derivatives and process for their preparation | Océ-Andeno B.V. (NL) | 1982-09-29 | — | — | EP | disclosed |
| JP-S55347-A | SYNTHETIC INTERMEDIATE FOR CEPHALOSPORIN ANALOGUE | SHIONOGI & CO LTD | 1980-01-05 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371310-A1 | MANDELIC ACID CONDENSATION POLYMERS | MSN, CHIA, CDC37 | CYP1A2 3512/4885CYP2C9 2519/4885KEAP1 1849/4885 |
| US-20170143757-A1 | MANDELIC ACID CONDENSATION POLYMERS | MSN, CHIA, CDC37 | CYP1A2 3512/4885CYP2C9 2519/4885KEAP1 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.