Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033050 | 0.89 | TP53 (0.55) | TP53MEN1KMT2AMAPTCDK1 | |
| SCHEMBL22081732 | 0.88 | MEN1 (0.50) | TP53MEN1KMT2AMAPTCDK1 | |
| SCHEMBL22033674 | 0.88 | TP53 (0.53) | TP53MEN1KMT2AMAPTCDK1 | |
| SCHEMBL22032869 | 0.86 | MEN1 (0.53) | TP53MEN1KMT2ACDK1CDK4 | |
| SCHEMBL22032948 | 0.86 | TP53 (0.54) | TP53MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22081753 | 0.86 | TP53 (0.52) | TP53MEN1KMT2AMAPTCDK1 | |
| SCHEMBL22033250 | 0.85 | TP53 (0.53) | TP53MEN1KMT2AMAPTKIF18A | |
| SCHEMBL22033354 | 0.85 | TP53 (0.59) | TP53MEN1KMT2AMAPTCDK1 | |
| SCHEMBL22033381 | 0.85 | RXFP1 (0.52) | TP53MEN1KMT2AKIF18ACSF1R | |
| SCHEMBL22032966 | 0.84 | KMT2A (0.51) | TP53MEN1KMT2AMAPTCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |