Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 11/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22084289 | 0.92 | MCHR1 (0.48) | NTRK1IRAK4MCHR1HDAC1KMT2A | |
| SCHEMBL22084290 | 0.89 | NTRK1 (0.44) | NTRK1IRAK4 | |
| SCHEMBL22083650 | 0.82 | NTRK1 (0.47) | NTRK1IRAK4HDAC6 | |
| SCHEMBL22083698 | 0.81 | NTRK1 (0.61) | NTRK1 | |
| SCHEMBL23408813 | 0.81 | NTRK1 (0.45) | NTRK1IRAK4 | |
| SCHEMBL22083691 | 0.81 | NTRK1 (0.44) | NTRK1IRAK4 | |
| SCHEMBL22084153 | 0.81 | ADRA1A (0.47) | NTRK1IRAK4MCHR1HDAC1KMT2A | |
| SCHEMBL14896935 | 0.80 | NTRK1 (0.46) | NTRK1IRAK4 | |
| SCHEMBL22084287 | 0.80 | NTRK1 (0.45) | NTRK1IRAK4 | |
| SCHEMBL23408737 | 0.78 | NTRK1 (0.40) | NTRK1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114465-A1 | PREPARATION AND APPLICATION OF HETEROAROMATIC IMINAZOLE COMPOUND | 上海轶诺药业有限公司 | 2020-06-11 | — | — | WO | disclosed |