Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22084391 | 0.98 | HPGD (0.39) | HPGDCA12CA9CA1CA2 | |
| SCHEMBL22084380 | 0.95 | HPGD (0.41) | HPGDCA12CA9CA1CA2 | |
| SCHEMBL22084393 | 0.85 | HPGD (0.40) | HPGDCA12CA9CA1CA2 | |
| SCHEMBL22084416 | 0.81 | HPGD (0.38) | HPGDCA12CA9CA1CA2 | |
| SCHEMBL22084382 | 0.81 | HPGD (0.38) | HPGDCA12CA9CA1CA2 | |
| SCHEMBL22084414 | 0.81 | LPL (0.43) | HPGDLMNA | |
| SCHEMBL22084696 | 0.81 | HPGD (0.45) | HPGDCA12CA9CA1CA2 | |
| SCHEMBL22084415 | 0.81 | HPGD (0.42) | HPGDMEN1KMT2ALMNAMAPT | |
| SCHEMBL22085424 | 0.76 | HPGD (0.49) | HPGDCA12CA9CA1CA2 | |
| SCHEMBL21724684 | 0.74 | KDM4E (0.48) | HPGDCA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117938-A1 | PRODRUGS OF ANTI-CANCER AND ANTI-AUTOIMMUNE DISEASES THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-06-11 | — | — | WO | disclosed |