Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22084427 | 0.83 | HPGD (0.40) | HPGDMEN1KMT2ACA12CA9 | |
| SCHEMBL22084380 | 0.82 | HPGD (0.41) | HPGDMEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL22084420 | 0.81 | HPGD (0.39) | HPGDMEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL22084415 | 0.81 | HPGD (0.42) | HPGDMEN1KMT2A | |
| SCHEMBL22084414 | 0.81 | LPL (0.43) | HPGD | |
| SCHEMBL22084391 | 0.81 | HPGD (0.39) | HPGDMEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL5115615 | 0.80 | HPGD (0.67) | HPGDMEN1KMT2ADAOMAPK1 | |
| SCHEMBL11315735 | 0.79 | HPGD (0.65) | HPGDMEN1KMT2ADAOMAPK1 | |
| Hydrogen Sulfide SCHEMBL27583640 | 0.79 | HPGD (0.65) | HPGDMEN1KMT2ADAOMAPK1 | |
| SCHEMBL22084393 | 0.78 | HPGD (0.40) | HPGDMEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117938-A1 | PRODRUGS OF ANTI-CANCER AND ANTI-AUTOIMMUNE DISEASES THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-06-11 | — | — | WO | disclosed |