Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.30 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692478 | 0.89 | HDAC6 (0.36) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL1696194 | 0.78 | HDAC6 (0.35) | HDAC1HDAC2HDAC6KCNQ4KCNQ5 | |
| SCHEMBL1207293 | 0.74 | CA14 (0.39) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL3530471 | 0.74 | CA14 (0.36) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL1743767 | 0.73 | HDAC6 (0.35) | CA14HDAC1HDAC2HDAC6KCNQ4 | |
| SCHEMBL10339672 | 0.72 | HDAC6 (0.37) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL16376128 | 0.72 | CA14 (0.39) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL29850241 | 0.72 | KCNQ4 (0.34) | CA14KCNQ4KCNQ5 | |
| SCHEMBL15285654 | 0.72 | — | — | |
| SCHEMBL30897721 | 0.72 | HDAC6 (0.34) | CA14HDAC1HDAC2HDAC6KCNQ4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114947-A1 | HETEROAROMATIC COMPOUNDS AS VANIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-06-11 | — | — | WO | disclosed |