SCHEMBL1207293

SCHEMBL1207293

C#CCN(CC#C)C(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 1/20 0.39
HDAC6 Q9UBN7 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
KCNQ4 P56696 3/20 0.36
KCNQ5 Q9NR82 3/20 0.36
SSTR4 P31391 1/20 0.31
HDAC3 O15379 1/20 0.31
NCOR2 Q9Y618 1/20 0.31
CTSD P07339 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3530471 0.90 CA14 (0.36) CA14HDAC6HDAC1HDAC2KCNQ4
SCHEMBL15503184 0.89 CTSK (0.35) CA14HDAC6HDAC1HDAC2KCNQ4
SCHEMBL1143116 0.87 SSTR4 (0.41) CA14HDAC6HDAC1HDAC2KCNQ4
SCHEMBL1688918 0.87 CA14 (0.35) CA14HDAC6HDAC1HDAC2KCNQ4
SCHEMBL1896934 0.87 CA14 (0.35) CA14HDAC6HDAC1HDAC2KCNQ4
SCHEMBL20029121 0.86 CA14 (0.34) CA14HDAC6HDAC1HDAC2KCNQ4
SCHEMBL13982487 0.86 CA14 (0.40) CA14HDAC6HDAC1HDAC2KCNQ4
SCHEMBL28733852 0.86 CA14 (0.37) CA14HDAC6HDAC1HDAC2KCNQ4
SCHEMBL4872179 0.84 DPP4 (0.39) CA14HDAC6HDAC1HDAC2KCNQ4
SCHEMBL6977019 0.84 CA14 (0.33) CA14HDAC6HDAC1HDAC2KCNQ4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMA INC (US) 2026-03-05 US disclosed
EP-4676922-A1 BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS Astrazeneca AB (SE) 2026-01-14 EP disclosed
WO-2025108411-A1 EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 北京沐华生物科技有限责任公司 2025-05-30 WO disclosed
WO-2024189488-A1 BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS ASTRAZENECA AB (SE) 2024-09-19 WO disclosed
US-20240190880-A1 SMALL MOLECULE DEGRADERS OF ESTROGEN RECEPTOR WITH CEREBLON LIGANDS REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-06-13 US disclosed
US-20240150360-A1 Small Molecule Degraders of CBP/p300 Proteins THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-05-09 US disclosed
WO-2024044098-A2 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-29 WO disclosed
US-11912702-B2 Substituted pyridines as inhibitors of histone deacetylase ALKERMES, INC. (US) 2024-02-27 US disclosed
US-11912702-B2 Substituted pyridines as inhibitors of histone deacetylase ALKERMES, INC. (US) 2024-02-27 US disclosed
WO-2024017372-A1 INDOLONE DERIVATIVE AND USE THEREOF 成都百裕制药股份有限公司 2024-01-25 WO disclosed
WO-2008044045-A1 PHARMACEUTICAL COMBINATIONS ASTEX THERAPEUTICS LIMITED (GB) 2008-04-17 WO disclosed
WO-2008044045-A1 PHARMACEUTICAL COMBINATIONS ASTEX THERAPEUTICS LIMITED (GB) 2008-04-17 WO disclosed
WO-2008044029-A1 PHARMACEUTICAL COMBINATIONS ASTEX THERAPEUTICS LIMITED (GB) 2008-04-17 WO disclosed
WO-2008044029-A1 PHARMACEUTICAL COMBINATIONS ASTEX THERAPEUTICS LIMITED (GB) 2008-04-17 WO disclosed
WO-2008044041-A1 PHARMACEUTICAL COMBINATIONS ASTEX THERAPEUTICS LIMITED (GB) 2008-04-17 WO disclosed
WO-2008044027-A2 PHARMACEUTICAL COMPOUNDS HAVING HSP90 INHIBITORY OR MODULATING ACTIVITY ASTEX THERAPEUTICS LIMITED (GB) 2008-04-17 WO disclosed
WO-2008044041-A1 PHARMACEUTICAL COMBINATIONS ASTEX THERAPEUTICS LIMITED (GB) 2008-04-17 WO disclosed
WO-2008044054-A2 HYDROXY-SUBSTITUTED BENZOIC ACID AMIDE COMPOUNDS FOR USE IN THERAPY ASTEX THERAPEUTICS LIMITED (GB) 2008-04-17 WO disclosed
WO-2006123242-A1 1, 2, 4 -TRIAZOLE DERIVATIVES AS VASOPRESSIN ANTAGONISTS PFIZER LIMITED (GB) 2006-11-23 WO disclosed
US-6200978-B1 FOR PREVENTING OR TREATING INFLAMMATORY DISEASES SUCH AS ARTHRITIS, PSORIASIS, ASTHMA, OR INFLAMMATORY BOWEL DISEASE, DISORDERS OF RESPIRATORY FUNCTION, GASTROINTESTINAL DISORDERS SUCH AS FUNCTIONAL BOWEL DISEASE, AS ANALGESICS PFIZER INC. 2001-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C9, SSB, C1S CA14 2417/4885HDAC6 576/4885HDAC1 1104/4885
US-20240150360-A1 Small Molecule Degraders of CBP/p300 Proteins EP300, CREBBP, NCOR1 CA14 3863/4885HDAC6 78/4885HDAC1 4/4885
US-11912702-B2 Substituted pyridines as inhibitors of histone deacetylase HDAC2, HDAC1, HDAC3 CA14 4233/4885HDAC6 9/4885HDAC1 2/4885
US-20240190880-A1 SMALL MOLECULE DEGRADERS OF ESTROGEN RECEPTOR WITH CEREBLON LIGANDS ESR1, CRBN, ESR2 CA14 753/4885HDAC6 4145/4885HDAC1 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.