Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.38 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.65 |
| ▸ | RAD52 | P43351 | 3/20 | 0.65 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.65 |
| ▸ | MC4R | P32245 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5476974 | 1.00 | HSP90AA1 (0.65) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL475770 | 1.00 | HSP90AA1 (0.65) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL9772817 | 1.00 | HSP90AA1 (0.65) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL694305 | 1.00 | HSP90AA1 (0.65) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL347739 | 1.00 | HSP90AA1 (0.65) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| SCHEMBL18280776 | 0.98 | DNM1 (0.63) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| SCHEMBL5274766 | 0.98 | DNM1 (0.63) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| SCHEMBL13766056 | 0.98 | DNM1 (0.63) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| SCHEMBL14340632 | 0.98 | DNM1 (0.63) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| SCHEMBL13766061 | 0.98 | DNM1 (0.63) | HSP90AA1RAD52PSMD14MMP2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703866-A | Polymer load and preparation method thereof | 中国石油天然气股份有限公司 | 2023-02-17 | — | — | CN | claimed |
| US-4234381-A | Fibrous material made with polymers stabilized by polymerizable vinyl benzyltrialkyl ammonium salt surfactant | ROHM AND HAAS COMPANY (US) | 1980-11-18 | — | — | US | claimed |
| US-4152201-A | SIZING | ROHM AND HAAS COMPANY (US) | 1979-05-01 | — | — | US | claimed |
| US-4017440-A | Polymers stabilized with polymerizable vinylbenzyltrialkyl ammonium salt surfactant | ROHM AND HAAS COMPANY (US) | 1977-04-12 | — | — | US | claimed |
| CN-115703866-B | Polymer load and preparation method thereof | 中国石油天然气股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-115703866-A | Polymer load and preparation method thereof | 中国石油天然气股份有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-114672053-A | Method for preparing anion exchange membrane based on ternary liquid crystal system | 山东大学 | 2022-06-28 | — | — | CN | disclosed |
| EP-1956899-B1 | COMPOSITIONS AND METHODS FOR CELL KILLING | OPLON PURE SCIENCE LTD (IL) | 2015-09-09 | — | — | EP | disclosed |
| EP-2421544-B1 | Microorganism comprising particles and uses of same | MENASHE OFIR (IL) | 2015-06-03 | — | — | EP | disclosed |
| US-8673606-B2 | Microorganism comprising particles and uses of same | MENASHE OFIR (IL) | 2014-03-18 | — | — | US | disclosed |
| US-7981408-B2 | Method of preserving food using antimicrobial packaging | BOSTON BRANDS, INC. (US) | 2011-07-19 | — | — | US | disclosed |
| US-20050271780-A1 | Method of preserving food using antimicrobial packaging | BOSTON BRANDS, INC. | 2005-12-08 | — | — | US | disclosed |
| US-4234381-A | Fibrous material made with polymers stabilized by polymerizable vinyl benzyltrialkyl ammonium salt surfactant | ROHM AND HAAS COMPANY (US) | 1980-11-18 | — | — | US | disclosed |
| US-4152201-A | SIZING | ROHM AND HAAS COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4017440-A | Polymers stabilized with polymerizable vinylbenzyltrialkyl ammonium salt surfactant | ROHM AND HAAS COMPANY (US) | 1977-04-12 | — | — | US | disclosed |