Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 17/20 | 0.60 |
| ▸ | THRA | P10827 | 16/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282663 | 0.89 | THRB (0.76) | THRBTHRAPTPN1ESR1ESR2 | |
| SCHEMBL22072187 | 0.84 | THRB (0.79) | THRBTHRAPTPN1ESR1ESR2 | |
| SCHEMBL13381711 | 0.84 | THRB (0.58) | THRBTHRAESR1ESR2 | |
| SCHEMBL22071770 | 0.79 | THRA (0.55) | THRBTHRA | |
| SCHEMBL282558 | 0.77 | THRB (0.49) | THRBTHRAESR1ESR2 | |
| SCHEMBL10274395 | 0.75 | THRB (1.00) | THRBTHRAPTPN1ESR1ESR2 | |
| SCHEMBL13381671 | 0.74 | THRB (0.83) | THRBTHRAPTPN1ESR1ESR2 | |
| SCHEMBL3156392 | 0.73 | THRB (0.58) | THRBTHRAPTPN1 | |
| SCHEMBL282128 | 0.72 | THRB (0.79) | THRBTHRAPTPN1 | |
| SCHEMBL328325 | 0.72 | THRB (1.00) | THRBTHRAPTPN1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117987-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISORDERS | VIKING THERAPEUTICS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |