Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12714959 | 0.85 | NR4A1 (0.52) | NR4A1MAOARAB9AMEN1NPC1 | |
| SCHEMBL28042792 | 0.85 | NR4A1 (0.52) | NR4A1MAOARAB9AMEN1NPC1 | |
| SCHEMBL4250239 | 0.83 | NR4A1 (0.59) | NR4A1MAOARAB9AMEN1NPC1 | |
| SCHEMBL4250235 | 0.83 | NR4A1 (0.59) | NR4A1MAOARAB9AMEN1NPC1 | |
| SCHEMBL12714966 | 0.82 | NR4A1 (0.49) | NR4A1MAOARAB9AMEN1NPC1 | |
| SCHEMBL3109223 | 0.80 | NR4A1 (0.55) | NR4A1MAOARAB9AMEN1NPC1 | |
| SCHEMBL9915224 | 0.80 | NR4A1 (0.55) | NR4A1MAOARAB9AMEN1NPC1 | |
| SCHEMBL12714965 | 0.80 | NR4A1 (0.55) | NR4A1MAOARAB9AMEN1NPC1 | |
| SCHEMBL8719353 | 0.80 | NR4A1 (0.55) | NR4A1MAOARAB9AMEN1NPC1 | |
| SCHEMBL13197243 | 0.77 | G6PC1 (0.58) | NR4A1MAOARAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020118597-A1 | PROCESS FOR MAKING 1- [ (3R, 4S) -4-CYANOTETRAHYDROPYRAN-3-YL] -3- [ (2-FLUORO-6-METHOXY-4-PYRIDYL) AMINO] PYRAZOLE-4-CARBOXAMIDE | INTERVET INTERNATIONAL B.V. (NL) | 2020-06-18 | — | — | WO | disclosed |