SCHEMBL4250239

SCHEMBL4250239

C(=NCCN=Cc1ccccn1)c1ccccn1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.59
MAOA P21397 2/20 0.57
RAB9A P51151 3/20 0.56
MEN1 O00255 2/20 0.56
NPC1 O15118 2/20 0.56
KMT2A Q03164 2/20 0.56
ATM Q13315 1/20 0.56
ALDH1A1 P00352 1/20 0.52
PKM P14618 1/20 0.52
USP2 O75604 1/20 0.52
G6PC1 P35575 1/20 0.51
MAOB P27338 1/20 0.46
TOP2A P11388 2/20 0.45
ADORA2A P29274 1/20 0.45
LMNA P02545 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
KDM4E B2RXH2 1/20 0.44
CTH P32929 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4250235 1.00 NR4A1 (0.59) NR4A1MAOARAB9AMEN1NPC1
SCHEMBL12714965 0.92 NR4A1 (0.55) NR4A1MAOARAB9AMEN1NPC1
SCHEMBL8719353 0.92 NR4A1 (0.55) NR4A1MAOARAB9AMEN1NPC1
SCHEMBL4255814 0.91 MAOA (0.53) NR4A1MAOARAB9AMEN1NPC1
SCHEMBL4254675 0.91 MAOA (0.53) NR4A1MAOARAB9AMEN1NPC1
SCHEMBL10308820 0.88 NR4A1 (0.52) NR4A1MAOARAB9AMEN1NPC1
SCHEMBL16293807 0.88 NR4A1 (0.52) NR4A1MAOARAB9AMEN1NPC1
SCHEMBL74245 0.88 NR4A1 (0.52) NR4A1MAOARAB9AMEN1NPC1
SCHEMBL9914146 0.88 NR4A1 (0.52) NR4A1MAOARAB9AMEN1NPC1
SCHEMBL28042792 0.88 NR4A1 (0.52) NR4A1MAOARAB9AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268933-B2 Polymers functionalized with polyimine compounds BRIDGESTONE CORPORATION (JP) 2012-09-18 US claimed
US-20090171035-A1 POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2009-07-02 US claimed
US-7470762-B2 Living radical polymerization of acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA (US) 2008-12-30 US claimed
US-7345127-B2 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA (US) 2008-03-18 US claimed
US-20080039601-A1 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA 2008-02-14 US claimed
US-20050131186-A1 Living radical polymerization of halogen-containing and acrylic monomers and the formation of block copolymers therefrom PENNSYLVANIA, UNIVERSITY OF 2005-06-16 US claimed
EP-0014062-B1 COMPOSITION AND PROCESS FOR THE IMPREGNATION AND SEALING OF POROUS ARTICLES LOCTITE (IRELAND) LIMITED (IE) 1984-03-07 EP claimed
EP-0014062-A1 Composition and process for the impregnation and sealing of porous articles LOCTITE (IRELAND) LIMITED (IE) 1980-08-06 EP claimed
US-8865794-B2 Anaerobic adhesive compositions having microencapsulated metal ions ND INDUSTRIES, INC. (US) 2014-10-21 US disclosed
US-8853352-B2 Functionalized polymer and method for making BRIDGESTONE CORPORATION (JP) 2014-10-07 US disclosed
US-8268933-B2 Polymers functionalized with polyimine compounds BRIDGESTONE CORPORATION (JP) 2012-09-18 US disclosed
US-20090171035-A1 POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2009-07-02 US disclosed
US-7470762-B2 Living radical polymerization of acrylic monomers and the formation of block copolymers therefrom UNIVERSITY OF PENNSYLVANIA (US) 2008-12-30 US disclosed
US-20080242764-A1 Such as iron oxide, copper naphthenate and/or cobalt naphthenate; more complete free radical curing polymerization with shorter curing time; bonding strength; joining wide variety of substrates without separate primer coating or other special treatment H.B. FULLER COMPANY 2008-10-02 US disclosed
US-5109036-A With alkysulfonylphenylhydrazine accelerator; storage stability CECA, S.A. (FR) 1992-04-28 US disclosed
EP-0443916-A1 Anaerobically curing adhesive compositions CECA S.A. (FR) 1991-08-28 EP disclosed
EP-0014062-B1 COMPOSITION AND PROCESS FOR THE IMPREGNATION AND SEALING OF POROUS ARTICLES LOCTITE (IRELAND) LIMITED (IE) 1984-03-07 EP disclosed
US-4416921-A AZONITRILE, ACRYLATE, A PHENOL, CHELATOR LOCTITE (IRELAND) LIMITED (IE) 1983-11-22 US disclosed
EP-0014062-A1 Composition and process for the impregnation and sealing of porous articles LOCTITE (IRELAND) LIMITED (IE) 1980-08-06 EP disclosed
US-4038475-A ACRYLATE MONOMER, PEROXY INITIATOR, SULFIMIDES, QUINONES, CHELATE COMPOUND LOCTITE CORPORATION (US) 1977-07-26 US disclosed