Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28751123 | 0.95 | ALDH1A1 (0.41) | ALDH1A1POLBKDM4ESMN1; SMN2GAA | |
| SCHEMBL5648255 | 0.76 | ALDH1A1 (0.41) | ALDH1A1POLBSMN1; SMN2GAAMEN1 | |
| SCHEMBL5650999 | 0.76 | ALDH1A1 (0.41) | ALDH1A1POLBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5648948 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1POLBSMN1; SMN2GAAMEN1 | |
| SCHEMBL22089817 | 0.76 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2GAAMEN1 | |
| SCHEMBL28650726 | 0.74 | ALDH1A1 (0.39) | ALDH1A1POLBKDM4ESMN1; SMN2GAA | |
| SCHEMBL16975547 | 0.73 | ALDH1A1 (0.50) | ALDH1A1POLBGAAMEN1MAPT | |
| SCHEMBL16975404 | 0.72 | ALDH1A1 (0.52) | ALDH1A1POLBGAAMEN1MAPT | |
| SCHEMBL27577341 | 0.71 | ALDH1A1 (0.36) | ALDH1A1POLBKDM4ESMN1; SMN2GAA | |
| SCHEMBL28334852 | 0.70 | ALDH1A1 (0.36) | ALDH1A1POLBKDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877381-A1 | BENZAMIDES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Lynk Pharmaceuticals Co. Ltd. (CN) | 2021-09-15 | — | — | EP | disclosed |
| WO-2020119819-A1 | BENZAMIDES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2020-06-18 | — | — | WO | disclosed |