Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | LIPA | P38571 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22089720 | 0.95 | ALDH1A1 (0.35) | ALDH1A1POLBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5650999 | 0.81 | ALDH1A1 (0.41) | ALDH1A1POLBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5648948 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5648255 | 0.81 | ALDH1A1 (0.41) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28650726 | 0.79 | ALDH1A1 (0.39) | ALDH1A1POLBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL16975404 | 0.77 | ALDH1A1 (0.52) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL27577341 | 0.76 | ALDH1A1 (0.36) | ALDH1A1POLBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL16975547 | 0.75 | ALDH1A1 (0.50) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL5646918 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27577342 | 0.72 | SMN1; SMN2 (0.44) | ALDH1A1KDM4ESMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1602191-A | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase | NOVO NORDISK AS (DK) | 2005-03-30 | — | — | CN | disclosed |