Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 3/20 | 0.56 |
| ▸ | KCNJ1 | P48048 | 9/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1641 | 0.91 | PRF1 (0.65) | PRF1KCNJ1KCNH2MAPTLMNA | |
| SCHEMBL29366960 | 0.91 | PRF1 (0.65) | PRF1KCNJ1KCNH2MAPTLMNA | |
| Benzonitrile SCHEMBL29071701 | 0.81 | MAOA (0.57) | PRF1KCNJ1KCNH2MAPTLMNA | |
| Toluene SCHEMBL28417431 | 0.81 | PRF1 (0.55) | PRF1KCNJ1KCNH2MAPTLMNA | |
| SCHEMBL22089880 | 0.80 | PRF1 (0.49) | PRF1KCNJ1KCNH2MAPTLMNA | |
| SCHEMBL148003 | 0.78 | PRF1 (0.54) | PRF1KCNJ1KCNH2MAPTLMNA | |
| SCHEMBL28914301 | 0.75 | PRF1 (0.59) | PRF1KCNJ1KCNH2MAPTLMNA | |
| SCHEMBL29933676 | 0.75 | PRF1 (0.59) | PRF1KCNJ1KCNH2MAPTLMNA | |
| SCHEMBL24442281 | 0.74 | MAPT (0.56) | PRF1KCNJ1KCNH2MAPTLMNA | |
| SCHEMBL13454843 | 0.72 | GRM5 (0.59) | PRF1MAPTLMNAGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113329994-A | Method for continuously preparing 5-cyanodiol | 浙江华海药业股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-111302971-A | Method for continuously preparing 5-cyanodiol | 上海奥博生物医药技术有限公司 | 2020-06-19 | — | — | CN | disclosed |
| WO-2020119507-A1 | METHOD FOR CONTINUOUSLY PREPARING 5-CITALOPRAM DIOL | 浙江华海药业股份有限公司 | 2020-06-18 | — | — | WO | disclosed |