Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22090143 | 0.85 | MEN1 (0.35) | GSK3BCCNT1CDK1CCNB1CDK9 | |
| SCHEMBL22089989 | 0.85 | PTK2 (0.39) | KCNMA1LCKGSK3BTSHRSMN1; SMN2 | |
| SCHEMBL18134016 | 0.77 | TSHR (0.47) | KCNMA1LCKGSK3BTSHRSMN1; SMN2 | |
| SCHEMBL18131712 | 0.74 | TSHR (0.45) | KCNMA1LCKGSK3BTSHRSMN1; SMN2 | |
| SCHEMBL15412383 | 0.74 | TSHR (0.45) | KCNMA1LCKGSK3BTSHRSMN1; SMN2 | |
| SCHEMBL30466489 | 0.74 | TSHR (0.45) | KCNMA1LCKGSK3BTSHRSMN1; SMN2 | |
| SCHEMBL21386640 | 0.74 | SMN1; SMN2 (0.50) | KCNMA1LCKTSHRSMN1; SMN2TDP1 | |
| SCHEMBL18131701 | 0.72 | TSHR (0.43) | KCNMA1LCKGSK3BTSHRSMN1; SMN2 | |
| SCHEMBL18131743 | 0.72 | TSHR (0.42) | KCNMA1LCKGSK3BTSHRSMN1; SMN2 | |
| SCHEMBL16665294 | 0.72 | TSHR (0.42) | KCNMA1LCKTSHRSMN1; SMN2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119606-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2020-06-18 | — | — | WO | disclosed |