Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22089634 | 0.86 | MAPK1 (0.45) | PTK2MAPK1ALDH1A1EGFRERBB2 | |
| SCHEMBL22090032 | 0.85 | KCNMA1 (0.44) | ALDH1A1KMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL18134016 | 0.75 | TSHR (0.47) | ALDH1A1KMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL18131690 | 0.73 | FGFR4 (0.50) | PTK2MAPK1ALDH1A1FGFR1FGFR3 | |
| SCHEMBL15412383 | 0.73 | TSHR (0.45) | ALDH1A1EGFRKMT2AL3MBTL1MEN1 | |
| SCHEMBL18131712 | 0.73 | TSHR (0.45) | ALDH1A1KMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL30466489 | 0.73 | TSHR (0.45) | ALDH1A1KMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL15413220 | 0.73 | FGFR4 (0.63) | FGFR1FGFR3FGFR2FGFR4KMT2A | |
| SCHEMBL15413168 | 0.72 | FGFR4 (0.60) | MAPK1ALDH1A1FGFR1FGFR4KMT2A | |
| SCHEMBL21386640 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1KMT2AL3MBTL1MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119606-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2020-06-18 | — | — | WO | disclosed |
| WO-2020119606-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2020-06-18 | — | — | WO | disclosed |