Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22090211 | 0.85 | KMT2A (0.54) | LMNAKMT2AKDM4ETP53MAPT | |
| SCHEMBL22090951 | 0.82 | KMT2A (0.56) | KMT2AKDM4EGAAMAPTNPSR1 | |
| SCHEMBL6875008 | 0.80 | KMT2A (0.53) | LMNAKMT2AKDM4EGAANPSR1 | |
| SCHEMBL22090226 | 0.78 | KDM4E (0.45) | LMNAKMT2AKDM4EGAATP53 | |
| SCHEMBL14335116 | 0.77 | KDM4E (0.59) | LMNAKMT2AKDM4EGAAMAPT | |
| SCHEMBL14055345 | 0.77 | KMT2A (0.59) | LMNAKMT2AKDM4EGAATP53 | |
| SCHEMBL22090036 | 0.77 | ESR1 (0.51) | LMNAKMT2AKDM4EMAPTNPSR1 | |
| SCHEMBL16555777 | 0.76 | KDM4E (0.52) | LMNAKMT2AKDM4EGAATP53 | |
| SCHEMBL5022435 | 0.76 | GAA (0.54) | LMNAKMT2AGAATP53MAPT | |
| SCHEMBL15536075 | 0.76 | LMNA (0.47) | LMNAKMT2AKDM4EGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894448-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020120227-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2020-06-18 | — | — | WO | disclosed |