SCHEMBL6875008

SCHEMBL6875008

O=C(Oc1ccccc1-c1ccccc1C(=O)O)c1cccc(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.53
KDM4E B2RXH2 4/20 0.53
GAA P10253 1/20 0.53
SLC6A3 Q01959 1/20 0.48
PTGER1 P34995 1/20 0.47
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
ALDH1A1 P00352 2/20 0.45
USP2 O75604 1/20 0.45
ALOX15 P16050 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
PYGL P06737 1/20 0.45
PYGM P11217 1/20 0.45
HSD17B10 Q99714 2/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
TOP1 P11387 1/20 0.44
GRM5 P41594 1/20 0.43
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6870248 0.85 SLC6A3 (0.63) KMT2AKDM4EGAASLC6A3ESR1
SCHEMBL6881505 0.85 KMT2A (0.59) KMT2AKDM4ESLC6A3PTGER1ESR1
SCHEMBL6865638 0.84 KMT2A (0.55) KMT2AKDM4EGAASLC6A3ESR1
SCHEMBL22090951 0.83 KMT2A (0.56) KMT2AKDM4EGAAESR1ESR2
SCHEMBL6872105 0.83 SLC6A3 (0.54) KMT2AKDM4EGAASLC6A3ESR1
SCHEMBL22090201 0.80 LMNA (0.53) KMT2AKDM4EGAAALDH1A1USP2
SCHEMBL21999712 0.79 KMT2A (0.70) KMT2AKDM4EGAAESR1ESR2
SCHEMBL6876187 0.79 ESR1 (0.55) KDM4EGAASLC6A3PTGER1ESR1
SCHEMBL11284614 0.78 HSD17B10 (0.62) KMT2AKDM4EGAASLC6A3ESR1
SCHEMBL7888315 0.77 PARP1 (0.49) KMT2AKDM4EGAAALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6720287-B2 WHEN AN AROMATIC DICARBOXYLATE IS ENCAPSULATEDTOGETHER WITH THE DIAZONIUM SALT COMPOUND, GENERATION OF PHOTODECOMPOSITION STAIN IS REDUCED AND SHELF LIFE IS IMPROVED FUJI PHOTO FILM CO., LTD. (JP) 2004-04-13 US disclosed
US-20030045426-A1 Heat sensitive recording material and microcapsule solution FUJI PHOTO FILM CO., LTD. 2003-03-06 US disclosed