Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | ACR | P10323 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321629 | 0.89 | PRSS1 (0.63) | KMT2ALMNANPC1RAB9ANR1I2 | |
| SCHEMBL16236368 | 0.87 | SLC6A3 (0.65) | KMT2AMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL22090309 | 0.84 | HTR1A (0.47) | KMT2ALMNAMAPTSMN1; SMN2PRSS1 | |
| SCHEMBL22090211 | 0.84 | KMT2A (0.54) | KMT2ALMNANPC1RAB9ANR1I2 | |
| SCHEMBL6881505 | 0.82 | KMT2A (0.59) | KMT2ALMNANPC1RAB9ANR1I2 | |
| SCHEMBL16238704 | 0.81 | PRSS1 (0.51) | KMT2ANPC1RAB9ASMN1; SMN2PRSS1 | |
| SCHEMBL22090282 | 0.80 | ESR1 (0.56) | KMT2ALMNANPC1RAB9ATP53 | |
| SCHEMBL12520418 | 0.79 | PRSS1 (0.73) | KMT2AMAPTSMN1; SMN2PRSS1ACR | |
| SCHEMBL8387767 | 0.79 | KMT2A (0.59) | KMT2ALMNANPC1RAB9ANR1I2 | |
| SCHEMBL22090213 | 0.78 | HPGD (0.59) | KMT2ANPC1RAB9ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894448-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020120227-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2020-06-18 | — | — | WO | disclosed |