Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL22091026

O=C(O)C(F)(F)F.O=c1ccc2ccccc2[nH]1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.69
CA9 Q16790 4/20 0.69
CA1 P00915 1/20 0.69
CA3 P07451 1/20 0.69
CA4 P22748 1/20 0.69
CA6 P23280 1/20 0.69
CA5A P35218 1/20 0.69
CA7 P43166 1/20 0.69
CA13 Q8N1Q1 1/20 0.69
CA14 Q9ULX7 1/20 0.69
CA5B Q9Y2D0 1/20 0.69
DAO P14920 2/20 0.43
HPGD P15428 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
SRD5A2 P31213 1/20 0.43
HSD17B10 Q99714 1/20 0.43
AR P10275 1/20 0.42
KIF11 P52732 1/20 0.41
FLT3 P36888 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL30219350 1.00 CA12 (0.69) CA12CA9CA1CA3CA4
Bicarbonate SCHEMBL7000646 0.87 CA12 (0.83) CA12CA9CA1CA3CA4
Oxalic Acid SCHEMBL4424852 0.85 CA12 (0.80) CA12CA9CA1CA3CA4
Acetic Acid SCHEMBL16395773 0.84 CA12 (0.77) CA12CA9CA1CA3CA4
Carbamic Acid SCHEMBL27418564 0.84 CA12 (0.77) CA12CA9CA1CA3CA4
SCHEMBL5437282 0.83 CA12 (1.00) CA12CA9CA1CA3CA4
SCHEMBL8621 0.83 CA12 (1.00) CA12CA9CA1CA3CA4
SCHEMBL29351086 0.83 CA12 (1.00) CA12CA9CA1CA3CA4
SCHEMBL30958273 0.83 CA12 (1.00) CA12CA9CA1CA3CA4
Trifluoromethanesulfonic Acid SCHEMBL2480378 0.81 CA12 (0.67) CA12CA9CA1CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3894398-A1 3,3-DIFLUOROALLYLAMINES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME Yuhan Corporation (KR) 2021-10-20 EP disclosed
WO-2020121261-A1 3,3-DIFLUOROALLYLAMINES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORPORATION (KR) 2020-06-18 WO disclosed