Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPRB | P23467 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPRG | P23470 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863984 | 0.78 | PTPN1 (0.51) | KCNN4PTPN2PTPN1PTPRBPTPRC | |
| SCHEMBL3971720 | 0.77 | HDAC3 (0.50) | KCNN4PTPN2PTPN1PTPRBPTPRC | |
| SCHEMBL27258934 | 0.76 | SMN1; SMN2 (0.51) | KCNN4PTPN2PTPN1PTPRBPTPRC | |
| SCHEMBL27655129 | 0.76 | ALDH1A1 (0.41) | KCNN4PTPN2PTPN1PTPRBPTPRC | |
| SCHEMBL24430199 | 0.76 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL9767865 | 0.76 | KCNN4 (0.46) | KCNN4PTPN2PTPN1PTPRBPTPRC | |
| SCHEMBL4956050 | 0.74 | RIPK1 (0.45) | KCNN4PTPN2PTPN1PTPRBPTPRC | |
| SCHEMBL16672977 | 0.74 | KCNN4 (0.44) | KCNN4PTPN2PTPN1PTPRBPTPRC | |
| SCHEMBL6344201 | 0.74 | SRC (0.45) | KCNN4PTPN2PTPN1PTPRBPTPRC | |
| SCHEMBL8493242 | 0.74 | KCNN4 (0.44) | KCNN4PTPN2PTPN1PTPRBPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020122182-A1 | AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF | 中外製薬株式会社 | 2020-06-18 | — | — | WO | disclosed |