Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092257 | 1.00 | PDE4D (0.38) | PDE4DHCRTR2MAPK1MEN1KMT2A | |
| SCHEMBL23922871 | 0.97 | PDE4D (0.40) | PDE4DHCRTR2MAPK1MEN1KMT2A | |
| SCHEMBL23922870 | 0.97 | PDE4D (0.40) | PDE4DHCRTR2MAPK1MEN1KMT2A | |
| SCHEMBL23922820 | 0.95 | HCRTR2 (0.36) | HCRTR2 | |
| SCHEMBL23922821 | 0.95 | HCRTR2 (0.36) | HCRTR2 | |
| SCHEMBL23922957 | 0.74 | HCRTR2 (0.35) | HCRTR2 | |
| SCHEMBL23922959 | 0.74 | HCRTR2 (0.35) | HCRTR2 | |
| SCHEMBL7303942 | 0.64 | PDE4D (0.51) | PDE4DMAPK1MEN1KMT2ALMNA | |
| SCHEMBL16454124 | 0.63 | PLAT (0.38) | PDE4DMEN1KMT2AALOX5PLAT | |
| SCHEMBL18361625 | 0.61 | DRD2 (0.49) | HCRTR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020122093-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 | 2020-06-18 | — | — | WO | disclosed |