Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 15/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23922959 | 1.00 | HCRTR2 (0.35) | HCRTR2S1PR5IDO1CARM1PRMT6 | |
| SCHEMBL23922860 | 0.81 | HCRTR2 (0.42) | HCRTR2 | |
| SCHEMBL23922858 | 0.81 | HCRTR2 (0.42) | HCRTR2 | |
| SCHEMBL23922821 | 0.79 | HCRTR2 (0.36) | HCRTR2DRD3 | |
| SCHEMBL23922820 | 0.79 | HCRTR2 (0.36) | HCRTR2DRD3 | |
| SCHEMBL23922871 | 0.76 | PDE4D (0.40) | HCRTR2 | |
| SCHEMBL23922870 | 0.76 | PDE4D (0.40) | HCRTR2 | |
| SCHEMBL22092257 | 0.74 | PDE4D (0.38) | HCRTR2 | |
| SCHEMBL22092258 | 0.74 | PDE4D (0.38) | HCRTR2 | |
| SCHEMBL29587157 | 0.69 | GABRA1 (0.39) | HCRTR2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896060-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2021-10-20 | — | — | EP | disclosed |