Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 10/20 | 0.84 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | CDK2 | P24941 | 8/20 | 0.69 |
| ▸ | CDK1 | P06493 | 5/20 | 0.69 |
| ▸ | CDK4 | P11802 | 5/20 | 0.69 |
| ▸ | CDK7 | P50613 | 5/20 | 0.69 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.69 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692762 | 0.92 | AURKA (1.00) | AURKAMAPTTP53MEN1KMT2A | |
| SCHEMBL22095314 | 0.91 | AURKA (0.76) | AURKAMAPTTP53MEN1KMT2A | |
| SCHEMBL22095574 | 0.90 | AURKA (0.70) | AURKAMAPTTP53MEN1KMT2A | |
| SCHEMBL22095014 | 0.89 | AURKA (0.80) | AURKAMAPTTP53MEN1KMT2A | |
| SCHEMBL22095046 | 0.89 | AURKA (0.81) | AURKAMAPTTP53MEN1KMT2A | |
| SCHEMBL22095059 | 0.89 | AURKA (0.67) | AURKAMAPTTP53MEN1KMT2A | |
| SCHEMBL22095290 | 0.88 | MEN1 (0.74) | AURKAMAPTTP53MEN1KMT2A | |
| SCHEMBL22095232 | 0.87 | AURKA (0.90) | AURKAMAPTTP53MEN1KMT2A | |
| SCHEMBL6680316 | 0.86 | AURKA (0.88) | AURKAMAPTTP53MEN1KMT2A | |
| SCHEMBL22095650 | 0.85 | AURKA (1.00) | AURKAMAPTTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548875-B2 | Inhibitor compounds for male contraception | UNIVERSITY OF WASHINGTON (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | UNIVERSITY OF WASHINGTON (US) | 2021-10-28 | — | — | US | disclosed |
| WO-2020123855-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | UNIVERSITY OF WASHINGTON (US) | 2020-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332030-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | ALDH1A1, ALDH3A1, ALDH16A1 | AURKA 3852/4885MAPT 4083/4885TP53 4039/4885 |
| US-11548875-B2 | Inhibitor compounds for male contraception | ALDH1A1, ALDH3A1, ALDH16A1 | AURKA 3852/4885MAPT 4083/4885TP53 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.