Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24137575 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL14177572 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL10943048 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL17090716 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL8205402 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL7547875 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL24488743 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL19414940 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL5365508 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL1458032 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10684281-B2 | Reversible surface functionalization | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-06-16 | — | — | US | disclosed |