Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18102798 | 0.84 | PAOX (0.44) | KDM4ELMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL18541636 | 0.81 | KDM4E (0.52) | MEN1KMT2AKDM4ELMNAL3MBTL1 | |
| SCHEMBL22430007 | 0.81 | KDM4E (0.52) | MEN1KMT2AKDM4ELMNAL3MBTL1 | |
| SCHEMBL1709091 | 0.81 | KDM4E (0.52) | MEN1KMT2AKDM4ELMNAL3MBTL1 | |
| SCHEMBL15056784 | 0.81 | KDM4E (0.52) | MEN1KMT2AKDM4ELMNAL3MBTL1 | |
| SCHEMBL22096301 | 0.81 | KDM4E (0.42) | MEN1KMT2AKDM4ELMNAL3MBTL1 | |
| SCHEMBL10337937 | 0.81 | KDM4E (0.54) | KDM4ELMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL22096294 | 0.81 | KDM4E (0.39) | KDM4ELMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL3680834 | 0.78 | KDM4E (0.52) | MEN1KMT2AKDM4ELMNAL3MBTL1 | |
| SCHEMBL22321686 | 0.78 | KDM4E (0.52) | MEN1KMT2AKDM4ELMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683379-B2 | Polymers, hydrogels, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683379-B2 | Polymers, hydrogels, and uses thereof | BOLA2; BOLA2B, PARG, BRAP | MEN1 2584/4885KMT2A 3896/4885KDM4E 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.