Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3373994 | 1.00 | KDM4E (0.52) | KDM4ELMNAL3MBTL1TDP1TSHR | |
| SCHEMBL22321686 | 1.00 | KDM4E (0.52) | KDM4ELMNAL3MBTL1TDP1TSHR | |
| Hydrochloric Acid SCHEMBL7165571 | 0.98 | KDM4E (0.50) | KDM4ELMNAL3MBTL1TDP1TSHR | |
| SCHEMBL4128441 | 0.94 | KDM4E (0.50) | KDM4ELMNAL3MBTL1TDP1TSHR | |
| SCHEMBL3801934 | 0.92 | KDM4E (0.48) | KDM4ELMNAL3MBTL1TDP1TSHR | |
| SCHEMBL8433089 | 0.92 | KDM4E (0.48) | KDM4ELMNAL3MBTL1TDP1TSHR | |
| SCHEMBL14118625 | 0.92 | KDM4E (0.48) | KDM4ELMNAL3MBTL1TDP1TSHR | |
| SCHEMBL12510924 | 0.92 | KDM4E (0.48) | KDM4ELMNAL3MBTL1TDP1TSHR | |
| SCHEMBL17678369 | 0.92 | KDM4E (0.48) | KDM4ELMNAL3MBTL1TDP1TSHR | |
| SCHEMBL617140 | 0.92 | KDM4E (0.48) | KDM4ELMNAL3MBTL1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087399-A1 | USE OF 9-OXOACRIDINE-10-ACETIC ACID, SALTS AND ESTERS THEREOF IN COMBINATION THERAPY OF OVARIAN CANCER | SURKOV KIRILL GENNADIEVICH | 2010-04-08 | — | — | US | disclosed |
| WO-2008121028-A2 | USE OF 9-OXOACRIDINE-10-ACETIC ACID, SALTS AND ESTERS THEREOF IN COMBINATION THERAPY OF OVARIAN CANCER | SURKOV KIRILL GENNEDIEVICH (RU) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008024026-A2 | USE OF 9-OXOACRIDINE-10-ACETIC ACID, ITS SALTS AND ESTERS FOR THE TREATMENT, PROPHYLAXIS OR RELAPSE PREVENTION OF PROSTATE CANCER | SURKOV KIRILL GENNADIEVICH (RU) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008024027-A2 | USE OF 9-OXOACRIDINE-10-ACETIC ACID, ITS SALTS AND ESTERS FOR ENHANCING THE EFFICACY OF ANTIANDROGENIC TREATMENT | SURKOV KIRILL GENNADIEVICH (RU) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087399-A1 | USE OF 9-OXOACRIDINE-10-ACETIC ACID, SALTS AND ESTERS THEREOF IN COMBINATION THERAPY OF OVARIAN CANCER | ACR, APEH, CA9 | KDM4E 2986/4885LMNA 3366/4885L3MBTL1 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.