Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044891 | 0.82 | KMT2A (0.54) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL10271603 | 0.78 | ALDH1A1 (0.41) | KMT2AMAPK1HIF1AMAPTALDH1A1 | |
| SCHEMBL7863860 | 0.77 | KMT2A (0.58) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL4271577 | 0.77 | KMT2A (0.58) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL19765234 | 0.76 | SLC2A1 (0.55) | MEN1KMT2ATSHRMAPK1NPSR1 | |
| SCHEMBL28407155 | 0.76 | KMT2A (0.47) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL17974815 | 0.75 | CYP19A1 (0.39) | MEN1KMT2ATSHRMAPK1CYP19A1 | |
| SCHEMBL11549277 | 0.74 | KMT2A (0.46) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL22096977 | 0.73 | POLB (0.45) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL22096978 | 0.73 | POLB (0.45) | MEN1KMT2ATSHRMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896053-A1 | METHOD FOR DIRECTLY CONSTRUCTING TETRA-SUBSTITUTED ALLENIC ACID COMPOUND HAVING HIGH OPTICAL ACTIVITY | Fudan University (CN) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020119549-A1 | METHOD FOR DIRECTLY CONSTRUCTING TETRA-SUBSTITUTED ALLENIC ACID COMPOUND HAVING HIGH OPTICAL ACTIVITY | 复旦大学 | 2020-06-18 | — | — | WO | disclosed |