SCHEMBL22097194

SCHEMBL22097194

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc4c(c3)c3ccccc3c3cc5oc6ccccc6c5cc43)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 10/20 0.44
▸ KMT2A Q03164 10/20 0.44
▸ MAPT P10636 8/20 0.44
▸ ALDH1A1 P00352 8/20 0.44
▸ HPGD P15428 8/20 0.44
▸ NTSR1 P30989 1/20 0.44
▸ KDM4E B2RXH2 5/20 0.42
▸ LMNA P02545 2/20 0.42
▸ AHR P35869 2/20 0.41
▸ GLA P06280 1/20 0.39
▸ MAOA P21397 1/20 0.38
▸ TTR P02766 1/20 0.38
▸ ADORA2A P29274 2/20 0.38
▸ ADORA1 P30542 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ CHEK2 O96017 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ PLA2G2A P14555 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22097206 0.97 MEN1 (0.45) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22097196 0.97 MEN1 (0.45) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22097284 0.96 MEN1 (0.44) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22096938 0.96 MEN1 (0.44) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22249700 0.94 KMT2A (0.46) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24169324 0.93 KMT2A (0.45) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL18960974 0.93 KMT2A (0.46) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24169360 0.93 KMT2A (0.45) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22249896 0.91 KMT2A (0.47) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL26704205 0.91 KMT2A (0.44) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11236075-B2 Organic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-02-01 — — US disclosed
US-20200190065-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11236075-B2 Organic compound and organic electroluminescence device using the same ICMT, OR10J3, PIEZO1 MEN1 1207/4885KMT2A 2500/4885MAPT 508/4885
US-20200190065-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME ICMT, OR10J3, PIEZO1 MEN1 1207/4885KMT2A 2500/4885MAPT 508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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