SCHEMBL220984

SCHEMBL220984

CC(C)c1ccccc1OP(=O)(Cl)Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
KCNK3 O14649 1/20 0.38
KCNK9 Q9NPC2 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
P2RX3 P56373 1/20 0.37
P2RX2 Q9UBL9 1/20 0.37
NISCH Q9Y2I1 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
RECQL P46063 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222948 0.89 LMNA (0.38) LMNAKMT2AMEN1KCNK3KCNK9
SCHEMBL18252 0.84 KMT2A (0.40) LMNAKMT2AMEN1KCNK3KCNK9
SCHEMBL29352226 0.84 KMT2A (0.40) LMNAKMT2AMEN1KCNK3KCNK9
SCHEMBL220985 0.81 KMT2A (0.37) LMNAKMT2AMEN1KCNK3KCNK9
SCHEMBL222949 0.81 KMT2A (0.37) LMNAKMT2AMEN1KCNK3KCNK9
SCHEMBL8016123 0.81 GABRA1 (0.38) LMNAKMT2AMEN1GABRA1GABRB2
SCHEMBL224271 0.81 INPPL1 (0.52) LMNAKMT2AMEN1KCNK3KCNK9
SCHEMBL2475805 0.81 GABRA1 (0.42) LMNAKMT2AMEN1KCNK3KCNK9
SCHEMBL8140422 0.81 NISCH (0.39) LMNAKMT2AMEN1GABRA1GABRB2
SCHEMBL29613140 0.81 INPPL1 (0.52) LMNAKMT2AMEN1KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3965220-A AMINE CATALYST MONSANTO COMPANY (US) 1976-06-22 US claimed
US-20140179811-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS HICKORY SPRINGS MFG CO (US) 2014-06-26 US disclosed
US-8575225-B2 Use of low triphenylphosphate, high phosphorous content isopropyl phenyl phosphates as flame retardants in polyurethane or polyisocyanurate foams HICKORY SPRINGS MANUFACTURING COMPANY (US) 2013-11-05 US disclosed
US-8350074-B2 Low triphenylphosphate, high phosphorous content isopropyl phenyl phosphates with high ortho alkylation ALBEMARLE CORPORATION (US) 2013-01-08 US disclosed
US-8143433-B2 Low triphenylphosphate, high phosphorous content isopropyl phenyl phosphates with high ortho alkylation ALBEMARLE CORPORATION (US) 2012-03-27 US disclosed
US-20120004438-A1 Low Triphenylphosphate, High Phosphorous Content Isopropyl Phenyl Phosphates With High Ortho Alkylation ALBEMARLE CORPORATION (US) 2012-01-05 US disclosed
US-20100130654-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN RESINS ALBEMARIE CORPORATION (US) 2010-05-27 US disclosed
US-20100120930-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS ALBEMARLE CORPORATION (US) 2010-05-13 US disclosed
US-20100012906-A1 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION ALBEMARLE CORPORATION (US) 2010-01-21 US disclosed
EP-2134782-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN RESINS Albemarle Corporation (US) 2009-12-23 EP disclosed
EP-2021347-A2 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION Albermarle Corporation (US) 2009-02-11 EP disclosed
WO-2008118695-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN RESINS ALBEMARLE CORPORATION (US) 2008-10-02 WO disclosed
WO-2008118699-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS ALBEMARLE CORPORATION (US) 2008-10-02 WO disclosed
WO-2007127691-A2 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION ALBERMARLE CORPORATION (US) 2007-11-08 WO disclosed
US-4144394-A FLAME RETARDANTS FOR POLYMERS MONSANTO COMPANY (US) 1979-03-13 US disclosed
US-4134877-A Flame retardant phosphoramidate compositions MONSANTO COMPANY (US) 1979-01-16 US disclosed
US-4124400-A Flame retardant polymer compositions MONSANTO COMPANY (US) 1978-11-07 US disclosed
US-4086302-A FLAME RETARDANTS MONSANTO COMPANY (US) 1978-04-25 US disclosed
US-4062909-A FIRE RETARDANTS MONSANTO COMPANY (US) 1977-12-13 US disclosed
US-3965220-A AMINE CATALYST MONSANTO COMPANY (US) 1976-06-22 US disclosed