Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | UNG | P13051 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27778427 | 0.98 | MAOA (0.42) | MAOAMAOBCDK1ALDH1A1PPARA | |
| SCHEMBL27799506 | 0.93 | MAOA (0.44) | MAOAMAOBCDK1ALDH1A1UNG | |
| SCHEMBL9559961 | 0.86 | MAOA (0.51) | MAOAMAOBCDK1ALDH1A1UNG | |
| SCHEMBL9480031 | 0.86 | MAOA (0.51) | MAOAMAOBCDK1ALDH1A1UNG | |
| SCHEMBL7640312 | 0.85 | MAOA (0.46) | MAOAMAOBALDH1A1UNG | |
| SCHEMBL5147572 | 0.83 | LPL (0.53) | PPARAPPARG | |
| SCHEMBL11440647 | 0.83 | LPL (0.53) | PPARAPPARG | |
| SCHEMBL7536683 | 0.83 | LPL (0.53) | PPARAPPARG | |
| SCHEMBL4083034 | 0.83 | LPL (0.53) | PPARAPPARG | |
| SCHEMBL1881521 | 0.83 | LPL (0.53) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666766-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |