SCHEMBL22099225

SCHEMBL22099225

Cc1ccc(C(=O)/C=C/c2ccc(-c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.89
MAOB P27338 7/20 0.77
MAOA P21397 4/20 0.77
POLB P06746 1/20 0.77
RAB9A P51151 1/20 0.77
ALDH1A1 P00352 4/20 0.74
HPGD P15428 3/20 0.74
CYP1B1 Q16678 2/20 0.74
CYP3A4 P08684 1/20 0.74
CYP1A1 P04798 1/20 0.69
PKM P14618 3/20 0.64
HTT P42858 2/20 0.64
ATM Q13315 2/20 0.64
NPSR1 Q6W5P4 2/20 0.64
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
NLRP1 Q9C000 1/20 0.64
LMNA P02545 1/20 0.64
NTSR1 P30989 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22098902 1.00 MAPT (0.89) MAPTMAOBMAOAPOLBRAB9A
4,4'-Dimethylchalcone SCHEMBL979560 0.94 MAPT (1.00) MAPTMAOBMAOAPOLBRAB9A
4,4'-Dimethylchalcone SCHEMBL979559 0.94 MAPT (1.00) MAPTMAOBMAOAPOLBRAB9A
SCHEMBL23789072 0.93 MAPT (0.87) MAPTMAOBMAOAPOLBRAB9A
SCHEMBL11814876 0.93 CYP1B1 (0.81) MAPTMAOBMAOAPOLBRAB9A
SCHEMBL10497980 0.93 CYP1B1 (0.81) MAPTMAOBMAOAPOLBRAB9A
Hydrochloric Acid SCHEMBL11819456 0.92 CYP1B1 (0.79) MAPTMAOBMAOAPOLBRAB9A
SCHEMBL27977352 0.91 MAPT (0.90) MAPTMAOBMAOAPOLBRAB9A
SCHEMBL10497491 0.87 MAPT (0.86) MAPTMAOBMAOAPOLBRAB9A
SCHEMBL8965069 0.87 MAPT (1.00) MAPTMAOBMAOAPOLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11299675-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2022-04-12 US disclosed
US-20200263089-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-08-20 US disclosed
US-20200190016-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190016-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE CNTN1, HVCN1, PKN1 MAPT 647/4885MAOB 3112/4885MAOA 3542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.