Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.33 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22099932 | 0.84 | KDM4E (0.35) | ALDH1A1HPGDKDM4ESMN1; SMN2TP53 | |
| SCHEMBL22100116 | 0.76 | KDM4E (0.34) | ALDH1A1HPGDKDM4ESMN1; SMN2HDAC3 | |
| SCHEMBL3486549 | 0.71 | ALDH1A1 (0.41) | NSD2ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL13692597 | 0.71 | KDM4E (0.39) | ALDH1A1HPGDKDM4ESMN1; SMN2CA2 | |
| SCHEMBL12708259 | 0.71 | MEN1 (0.56) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL1584943 | 0.69 | MEN1 (0.57) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL14669007 | 0.69 | SMN1; SMN2 (0.51) | ALDH1A1HPGDSMN1; SMN2MAPK1TP53 | |
| SCHEMBL16549869 | 0.69 | SMN1; SMN2 (0.48) | ALDH1A1HPGDSMN1; SMN2MAPK1TP53 | |
| SCHEMBL22124710 | 0.68 | NPC1 (0.58) | ALDH1A1HPGDSMN1; SMN2MAPK1TP53 | |
| SCHEMBL16329591 | 0.68 | SMN1; SMN2 (0.50) | ALDH1A1HPGDSMN1; SMN2MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976081-B1 | METHODS OF ACUTE RESTORATION OF VASCULAR COMPLIANCE | ALUMEND LLC (US) | 2020-06-17 | — | — | EP | disclosed |