Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113644 | 0.83 | ALDH1A1 (0.47) | ALDH1A1GLAKEAP1NFE2L2CRHBP | |
| SCHEMBL29679602 | 0.83 | ALDH1A1 (0.47) | ALDH1A1GLAKEAP1NFE2L2CRHBP | |
| SCHEMBL7536538 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GLAKEAP1NFE2L2KDM4E | |
| SCHEMBL11780262 | 0.77 | CDC25B (0.46) | ALDH1A1GLAKEAP1NFE2L2CRHBP | |
| SCHEMBL3293879 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GLAKDM4EGAAMAPT | |
| SCHEMBL13541560 | 0.73 | NR4A1 (0.46) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL4954609 | 0.72 | PARP1 (0.41) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL22100012 | 0.71 | NSD2 (0.39) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL6061358 | 0.71 | ALDH1A1 (0.56) | ALDH1A1GLAKEAP1KDM4EGAA | |
| SCHEMBL7536533 | 0.70 | KMT2A (0.56) | ALDH1A1KDM4EGAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279967-A | Using fluorophore label | NALCO CHEMICAL COMPANY (US) | 1994-01-18 | — | — | US | claimed |
| US-20100035281-A1 | COMPOSITIONS AND METHODS FOR TISSUE-BASED PROTEIN TRUNCATION TEST FOR DISEASE DIAGNOSIS | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035281-A1 | COMPOSITIONS AND METHODS FOR TISSUE-BASED PROTEIN TRUNCATION TEST FOR DISEASE DIAGNOSIS | PMP22, PABPC4, PABPC1 | ALDH1A1 4348/4885GLA 1948/4885KEAP1 4638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.