Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201324 | 0.87 | FGFR1 (0.58) | FGFR1NPC1RAB9AALOX5MAOB | |
| SCHEMBL19217080 | 0.82 | ALOX5 (0.42) | NPC1RAB9AALOX5MAOBMAOA | |
| SCHEMBL10269114 | 0.82 | FGFR1 (0.58) | FGFR1METAP2FGFR2FGFR3CDK2 | |
| SCHEMBL19368366 | 0.81 | KDM4E (0.49) | NPC1RAB9AALOX5MAOBADRA2A | |
| SCHEMBL23206844 | 0.79 | ALOX5 (0.44) | NPC1RAB9AALOX5MAOBMAOA | |
| SCHEMBL20466823 | 0.79 | HDAC6 (0.43) | NPC1RAB9AALOX5MAOBMAOA | |
| SCHEMBL13201323 | 0.77 | GSK3B (0.58) | FGFR1NPC1RAB9AALOX5MAOB | |
| SCHEMBL19579012 | 0.76 | DYRK1A (0.46) | NPC1RAB9AALOX5MAOBMAOA | |
| SCHEMBL22221986 | 0.76 | FGFR1 (0.43) | FGFR1NPC1RAB9AFGFR2FGFR3 | |
| SCHEMBL19492650 | 0.76 | FGFR1 (0.43) | FGFR1NPC1RAB9AFGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200188535-A1 | Bioorthogonal Turn-on Probes | THE GENERAL HOSPITAL CORPORATION | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200188535-A1 | Bioorthogonal Turn-on Probes | ZYX, MPI, BAZ1A | FGFR1 217/4885NPC1 2002/4885RAB9A 2062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.