Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425857 | 0.83 | TRPM8 (0.61) | TRPM8TP53HPGD | |
| SCHEMBL11695822 | 0.83 | TRPM8 (1.00) | TRPM8ALDH1A1RAB9AHPGDTRPA1 | |
| SCHEMBL9425793 | 0.78 | HPGD (0.58) | TRPM8HPGD | |
| SCHEMBL22109121 | 0.78 | TRPM8 (0.61) | TRPM8ALDH1A1RAB9AHPGDTSHR | |
| SCHEMBL9425573 | 0.77 | TRPM8 (0.64) | TRPM8ALDH1A1HPGDKMT2A | |
| SCHEMBL9426557 | 0.77 | TRPM8 (0.57) | TRPM8HPGD | |
| SCHEMBL6332632 | 0.77 | TRPM8 (0.52) | TRPM8ALDH1A1MAPTL3MBTL1RAB9A | |
| SCHEMBL9425769 | 0.77 | TRPM8 (0.67) | TRPM8ALDH1A1RAB9A | |
| SCHEMBL9425976 | 0.76 | TRPM8 (0.62) | TRPM8ALDH1A1MAPTRAB9AHPGD | |
| SCHEMBL9788827 | 0.75 | TRPM8 (0.62) | TRPM8ALDH1A1MAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |