Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349898 | 0.89 | TRPM8 (0.62) | TRPM8RAB9ACYP3A4HDAC1HDAC2 | |
| SCHEMBL9425573 | 0.87 | TRPM8 (0.64) | TRPM8CYP3A4HDAC1HDAC2HDAC3 | |
| SCHEMBL9425769 | 0.87 | TRPM8 (0.67) | TRPM8RAB9ACYP3A4HDAC1HDAC2 | |
| SCHEMBL9425857 | 0.82 | TRPM8 (0.61) | TRPM8CYP3A4HDAC1HDAC2HDAC3 | |
| SCHEMBL9425793 | 0.80 | HPGD (0.58) | TRPM8HDAC1HDAC2HDAC3HDAC6 | |
| SCHEMBL13545151 | 0.80 | TRPM8 (0.57) | TRPM8CYP3A4HDAC1HDAC2HDAC3 | |
| SCHEMBL29364835 | 0.79 | CYP3A4 (0.62) | TRPM8CYP3A4HDAC1HDAC2HDAC3 | |
| SCHEMBL7406 | 0.79 | CYP3A4 (0.62) | TRPM8CYP3A4HDAC1HDAC2HDAC3 | |
| SCHEMBL9426166 | 0.79 | TRPM8 (0.48) | TRPM8RAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL9426557 | 0.79 | TRPM8 (0.57) | TRPM8HDAC1HDAC2HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338745-A | Alzheimer's disease | MITSUI TOATSU CHEMICALS, INCORPORATION (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0495998-A1 | DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND APPLICATION THEREOF AS MEDICINE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-29 | — | — | EP | disclosed |