Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 3/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | MAP3K8 | P41279 | 5/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101389 | 0.91 | EGFR (0.41) | EGFRERBB2TDO2ABCG2MAP3K8 | |
| SCHEMBL22101890 | 0.81 | ABCG2 (0.41) | EGFRERBB2TDO2ABCG2KDR | |
| SCHEMBL22101880 | 0.76 | AR (0.41) | EGFRERBB2ABCG2MAP3K8AR | |
| SCHEMBL22393602 | 0.75 | TAS2R14 (0.44) | EGFRERBB2KDRARBRAF | |
| SCHEMBL22393849 | 0.75 | ABCG2 (0.35) | EGFRABCG2KDRARNTSR1 | |
| SCHEMBL22101394 | 0.65 | BRAF (0.33) | TDO2BRAF | |
| SCHEMBL22101280 | 0.63 | TAS2R14 (0.52) | KDRARBRAF | |
| SCHEMBL3938525 | 0.62 | TRPV1 (0.68) | — | |
| SCHEMBL3289311 | 0.59 | AR (0.52) | AR | |
| SCHEMBL3057215 | 0.58 | AR (0.55) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |