Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101537 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL22101469 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL22393592 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL22393590 | 0.77 | ELANE (0.32) | — | |
| SCHEMBL22101697 | 0.76 | KCNQ3 (0.34) | HPGDHSD17B10TP53 | |
| SCHEMBL24425377 | 0.73 | HSD17B10 (0.41) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL22101877 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL22101465 | 0.72 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL22101918 | 0.69 | MAPT (0.35) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL17808956 | 0.68 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |