Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101522 | 0.82 | PIK3CB (0.37) | KCNQ3KCNQ2RAD51PIK3CB | |
| SCHEMBL22101486 | 0.79 | KCNQ3 (0.35) | KCNQ3KCNQ2RAD51 | |
| SCHEMBL22101454 | 0.79 | KCNQ3 (0.35) | KCNQ3KCNQ2RAD51 | |
| SCHEMBL22393588 | 0.79 | KCNQ3 (0.36) | KCNQ3KCNQ2RAD51 | |
| SCHEMBL22101698 | 0.76 | KDM4E (0.39) | TP53HPGDHSD17B10 | |
| SCHEMBL22393590 | 0.76 | ELANE (0.32) | TSHR | |
| SCHEMBL25105584 | 0.72 | EGFR (0.31) | — | |
| SCHEMBL22101865 | 0.71 | KCNQ3 (0.31) | KCNQ3KCNQ2RAD51PIK3CB | |
| SCHEMBL19836282 | 0.70 | EGFR (0.37) | — | |
| SCHEMBL22101455 | 0.70 | P2RX3 (0.36) | PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |