Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 8/20 | 0.47 |
| ▸ | PIM1 | P11309 | 8/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 8/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.47 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 3/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800642 | 0.87 | PARP1 (0.43) | CDC7PIM1CSNK2BCSNK2A1TMIGD3 | |
| SCHEMBL27242013 | 0.87 | PARP1 (0.43) | CDC7PIM1CSNK2BCSNK2A1TMIGD3 | |
| SCHEMBL23293951 | 0.79 | KDM4E (0.47) | — | |
| SCHEMBL22101466 | 0.75 | PARP1 (0.37) | PIM1CSNK2BTNKSTNKS2PARP1 | |
| SCHEMBL25795251 | 0.73 | CDC7 (0.38) | CDC7PIM1CSNK2BCSNK2A1TMIGD3 | |
| SCHEMBL30783587 | 0.73 | CDC7 (0.40) | CDC7PIM1CSNK2BCSNK2A1TMIGD3 | |
| SCHEMBL22101792 | 0.73 | PIM1 (0.38) | CDC7PIM1CSNK2BCSNK2A1TNKS | |
| SCHEMBL22393820 | 0.73 | PKM (0.46) | PIM1CSNK2BCSNK2A1TNKSTNKS2 | |
| SCHEMBL22600708 | 0.72 | CDC7 (0.37) | CDC7PIM1CSNK2BCSNK2A1TMIGD3 | |
| SCHEMBL22101365 | 0.72 | PARP1 (0.47) | PIM1CSNK2BADORA1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |