Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101466 | 0.78 | PARP1 (0.37) | PIM1CSNK2BHTTPARP1PARP2 | |
| SCHEMBL22393820 | 0.75 | PKM (0.46) | PIM1CSNK2BCSNK2A1HCAR2PARP1 | |
| SCHEMBL22101302 | 0.75 | GAA (0.51) | PIM1CSNK2BCDC7CSNK2A1HTT | |
| SCHEMBL22393695 | 0.74 | PARP2 (0.38) | CSNK2BHCAR2HTTPARP1PARP2 | |
| SCHEMBL22101365 | 0.74 | PARP1 (0.47) | PIM1CSNK2BHTTPARP1PARP2 | |
| SCHEMBL22101758 | 0.73 | CDC7 (0.47) | PIM1CSNK2BCDC7CSNK2A1PARP1 | |
| SCHEMBL22101861 | 0.73 | PARP1 (0.42) | PIM1HCAR2HTTPARP1PARP2 | |
| SCHEMBL6979552 | 0.72 | PPARG (0.46) | PIM1CSNK2BCDC7CSNK2A1HTT | |
| SCHEMBL22101891 | 0.71 | KDM4C (0.46) | HCAR2HTTPARP1PARP2TNKS | |
| SCHEMBL18130618 | 0.69 | IP6K1 (0.56) | PIM1CSNK2BCDC7CSNK2A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |