Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226647 | 0.79 | PIM1 (0.41) | PIM1PIM3CHEK1AKT1FLT3 | |
| SCHEMBL2418830 | 0.76 | NQO2 (0.38) | PIM1PIM3CHEK1AKT1FLT3 | |
| SCHEMBL31056362 | 0.76 | NQO2 (0.38) | PIM1PIM3CHEK1AKT1FLT3 | |
| SCHEMBL20680534 | 0.75 | PARP1 (0.39) | PIM1PIM3CHEK1AKT1FLT3 | |
| SCHEMBL16112933 | 0.74 | PARP1 (0.70) | PIM1PIM3CHEK1AKT1FLT3 | |
| SCHEMBL5370069 | 0.73 | PARP1 (0.54) | CHEK1PARP1PDPK1 | |
| SCHEMBL22492390 | 0.71 | CCR8 (0.48) | PIM3ALDH1A1KMT2AHPGD | |
| SCHEMBL1144808 | 0.71 | GSK3B (0.36) | GSK3B | |
| SCHEMBL17030854 | 0.70 | PARP1 (0.37) | PIM1CHEK1PARP1ALDH1A1PDPK1 | |
| SCHEMBL22101759 | 0.69 | ADORA1 (0.46) | PARP1ALDH1A1PARP2PARP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |