Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2418830 | 1.00 | NQO2 (0.38) | NQO2CHEK1PIM1AKT1FLT3 | |
| SCHEMBL8404371 | 0.79 | PARP1 (0.43) | CHEK1PIM1MEN1KMT2APARP1 | |
| SCHEMBL24224423 | 0.77 | ADRA2A (0.37) | CHEK1PIM1HTR1DHTR1BPARP1 | |
| SCHEMBL30140704 | 0.76 | CHEK1 (0.37) | CHEK1PIM1AKT1FLT3PIM3 | |
| SCHEMBL18554387 | 0.76 | MAPT (0.39) | CHEK1PIM1AKT1FLT3PIM3 | |
| SCHEMBL23749628 | 0.76 | CHEK1 (0.37) | CHEK1PIM1AKT1FLT3PIM3 | |
| SCHEMBL2411729 | 0.76 | MAPT (0.39) | CHEK1PIM1AKT1FLT3PIM3 | |
| SCHEMBL29260807 | 0.76 | ALDH1A1 (0.41) | CHEK1PIM1RAB9ACSNK2A1PARP1 | |
| SCHEMBL29260806 | 0.76 | ALDH1A1 (0.41) | CHEK1PIM1RAB9ACSNK2A1PARP1 | |
| SCHEMBL7090538 | 0.76 | PRKCI (0.41) | CHEK1PIM1PARP1RPS6KA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |