Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.55 |
| ▸ | RBP4 | P02753 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3309889 | 0.81 | KMT2A (0.70) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30477850 | 0.81 | KMT2A (0.70) | KMT2ARBP4MEN1CYP1A2CYP3A4 | |
| SCHEMBL15294735 | 0.81 | KMT2A (0.70) | KMT2ARBP4MEN1CYP1A2CYP3A4 | |
| SCHEMBL17746092 | 0.80 | KMT2A (0.68) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11399275 | 0.80 | KMT2A (0.68) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31057148 | 0.80 | KMT2A (0.68) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24297726 | 0.80 | KMT2A (0.68) | KMT2ARBP4TTRMEN1CYP1A2 | |
| SCHEMBL16034182 | 0.80 | KMT2A (0.68) | KMT2ARBP4TTRMEN1CYP1A2 | |
| SCHEMBL11279016 | 0.78 | KMT2A (0.62) | KMT2ARBP4TTRMEN1CYP1A2 | |
| SCHEMBL1264645 | 0.75 | KMT2A (0.66) | KMT2ARBP4TTRMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190083-A1 | LIBRARIES OF PYRIDINE-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190083-A1 | LIBRARIES OF PYRIDINE-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | VDR, TRPM8, TRPM7 | KMT2A 4027/4885PRKCQ 1101/4885RBP4 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.