Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699564 | 0.81 | TAAR1 (0.55) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL30288127 | 0.81 | FFAR1 (0.59) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL455219 | 0.81 | FFAR1 (0.59) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL27503091 | 0.80 | FFAR1 (0.48) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL16239236 | 0.79 | FFAR1 (0.58) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL22102704 | 0.79 | KDM4E (0.50) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL22089619 | 0.79 | FFAR1 (0.47) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL29660459 | 0.79 | FFAR1 (0.47) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL17605074 | 0.79 | FFAR1 (0.47) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| Ethane SCHEMBL10497410 | 0.78 | FFAR1 (0.56) | FFAR1PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119592-A1 | NOVEL THREE-RING FUSED STRUCTURE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 信达生物制药(苏州)有限公司 | 2020-06-18 | — | — | WO | disclosed |