Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22102873 | 0.88 | CSF1R (0.37) | L3MBTL1PSMD14POLBMAPTMAPK1 | |
| SCHEMBL22075152 | 0.70 | PSMD14 (0.40) | ALDH1A1L3MBTL1KMT2APSMD14HPGD | |
| SCHEMBL28647317 | 0.68 | PSMD14 (0.49) | ALDH1A1L3MBTL1KMT2APSMD14MEN1 | |
| SCHEMBL3860359 | 0.67 | KDM4E (0.51) | ALDH1A1L3MBTL1KMT2APSMD14MEN1 | |
| SCHEMBL22074907 | 0.67 | PSMD14 (0.48) | ALDH1A1L3MBTL1KMT2APSMD14MEN1 | |
| SCHEMBL26009759 | 0.67 | PSMD14 (0.48) | ALDH1A1L3MBTL1KMT2APSMD14MEN1 | |
| SCHEMBL22074963 | 0.67 | PSMD14 (0.48) | ALDH1A1L3MBTL1PSMD14POLBMAPT | |
| SCHEMBL31606412 | 0.66 | PSMD14 (0.47) | ALDH1A1L3MBTL1KMT2APSMD14MAPT | |
| SCHEMBL22074944 | 0.65 | NPC1 (0.38) | PSMD14MAPTHPGDALOX15HTT | |
| SCHEMBL2031896 | 0.65 | ALOX15 (0.65) | ALDH1A1L3MBTL1KMT2APSMD14HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123453-A2 | ALK5 INHIBITORS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2020-06-18 | — | — | WO | disclosed |